Download PDFAuthors having equal contributions.
Accepted 16 December 2020
Available Online 18 January 2021
- DOI
- https://doi.org/10.2991/mathi.k.201218.001
- Keywords
- Tympanic membrane
auditory canal
tissue engineering
biomaterials
cells
growth factors
stem cells - Abstract
The impairment in the Tympanic Membrane (TM) and the External Auditory Canal (EAC) results in otitis media, tympanos-clerosis, and perforations. The resulting reverberation of these pathologies is the loss of hearing, which eventually requires surgical treatment. The gold standard for the surgical procedures, autologous temporalis fascia, is reported with limited success. In recent times the biomaterial substitutes for this very purpose have carried off tremendous interest. The current review explicitly focuses on the last 10 years reports describing TM and EAC regeneration by biomaterial intervention. This review also provides an intelligible insight into various fabrication techniques for grafting to mimic TM-collagen’s radial and circular patterns. In the end, we have reached the terms by highlighting the future of the biomaterials in contrast to the current challenges in TM and EAC regeneration. Overall, the review will be a better source for developing futuristic biomaterials for the discussed problem.
- Copyright
- © 2021 The Authors. Published by Atlantis Press B.V.
- Open Access
- This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite This Article
TY - JOUR AU - Deepak Ranglani AU - Shubham Agiwal AU - Namdev More AU - Rohit Parkale AU - Vaibhav Shitole AU - Aishwarya Rajaram Hiray AU - Govinda Kapusetti PY - 2021 DA - 2021/01/18 TI - Review on Tympanic Membrane and Auditory Canal Regeneration by Biomaterial Intervention JO - Materials Highlights SP - 7 EP - 17 VL - 2 IS - 1-2 SN - 2666-4933 UR - https://doi.org/10.2991/mathi.k.201218.001 DO - https://doi.org/10.2991/mathi.k.201218.001 ID - Ranglani2021 ER -
copy
